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B-cell maturation antigen (BCMA or BCM) also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is a protein that in humans is encoded by the TNFRSF17 gene TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF)
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Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth metastasis and tumor angiogenesis Nectin-2 expression in ovarian cancer may support tumor cell adhesion leading to growth and lymph node metastasis Effect of VEGF on Nectin-2 expression as well as permeability was investigated in HUVEC
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Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF) Although it has been proposed that mesothelin may be involved in cell adhesion its biological function is not known A knockout mouse line that lacks mesothelin reproduces and develops normally
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LILRB4 also known as CD85k and LIR-5 ILT3 is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains a 21 aa transmembrane segment and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM) LILRB4 is receptor for class I MHC antigens Recognizes a broad spectrum of HLA-A HLA-B HLA-C and HLA-G alleles
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His-Tag Protein Purification Column (Pre-packed, 5 x 5ml) - AminTrap (ab270529) is a simple and easy ready to use chromatography medium for purifying His-tagged proteins that have been expressed in series of expression vectors, such as E.coli., yeast, insect cells and mammalian cells.
This histidine (HIS) tagged human IgG1 F(ab) isotype control is the F(ab) region only and reacts with hen egg lysozyme. It is a recombinant HIS human IgG1 F(ab) produced in CHO cells, designed with low or no specific binding to human samples.
Isotype: Human IgG1, κ
Formulation: PBS, pH 7.0, no stabilizers or preservatives
Endotoxin: ≤0.5 EU/mg
Purity: ≥95% determined by SDS-PAGE
Sterility: 0.2 μm filtration
Molecular Weight: 50 kDa
Storage: Store at 4°C, do not freeze
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